An novel approach (aMAP, ancestry of Modern Admixed Populations) for inferring local phased ancestry
Ma Y, Zhao J, Wong JS, Ma L, Li W, Fu G, Xu W, Zhang K, Kittles RA, Li Y, Song Q. Accurate inference of local phased ancestry of modern admixed populations. Scientific Reports. 2014 Jul 23;4:5800. PMID:25052506
Determines the haplotypes of each person from unphased high-throughput genotypes in family pedigrees. This method features high accuracy, chromosome-range phasing distance, linear computing, flexible pedigree types and flexible genetic marker types.
Li W, Fu G, Rao W, Xu W, Ma L, Shiwen Guo and Qing Song. GenomeLaser: fast and accurate haplotyping from pedigree genotypes. Bioinformatics. 2015 Dec 15; 31(24): 3984–3987. PMCID: PMC5013932
Using limited experimental seed data, HiFi can yield two integral, high-resolution personal chromosomal haplotypes in a cost- and time-efficient manner.
Rao W, Ma Y, Ma L, Zhao J, Li Q, Gu W, Zhang K, Vincent C Bond, and Qing Song. High-resolution whole-genome haplotyping using limited seed data. Nat Methods. 2013 Jan; 10(1): 10.1038/nmeth.2308. PMCID: PMC3835542